Cardiosphere-Derived Cells: A Possible Source for Regenerative Cell Therapy in Congenital Heart Diseases
نویسندگان
چکیده
منابع مشابه
Cardiosphere-derived cells for heart regeneration.
www.thelancet.com Vol 379 June 30, 2012 2425 2 Lemos B, Araripe LO, Hartl DL. Polymorphic Y chromosomes harbor cryptic variation with manifold functional consequences. Science 2008; 319: 91–93. 3 Lemos B, Branco AT, Hartl DL. Epigenetic eff ects of polymorphic Y chromosomes modulate chromatin components, immune response, and sexual confl ict. Proc Natl Acad Sci USA 2010; 107: 15826–31. 4 Spach ...
متن کاملSpermatogonia stem cells: A new pluripotent source for repairment in regenerative medicine
Recently new reports have proved the pluripotency of spermatogonial stem cells (SSCs) derived from male gonad. This pluripotent stem cells resembled Embryonic stem cells recognized as Embryonic Stem like cells (ES like cells). ES like cells forms sharp edge colonies that are immunopositive to pluripotency markers and have differentiation capacity to Ectodermal, Mesodermal and Endodermal layers....
متن کاملSafety and efficacy of allogeneic cell therapy in infarcted rats transplanted with mismatched cardiosphere-derived cells.
BACKGROUND Cardiosphere-derived cells (CDCs) are an attractive cell type for tissue regeneration, and autologous CDCs are being tested clinically. However, autologous therapy necessitates patient-specific tissue harvesting and cell processing, with delays to therapy and possible variations in cell potency. The use of allogeneic CDCs, if safe and effective, would obviate such limitations. We com...
متن کاملUrine-derived stem cells: A novel and versatile progenitor source for cell-based therapy and regenerative medicine.
Engineered functional organs or tissues, created with autologous somatic cells and seeded on biodegradable or hydrogel scaffolds, have been developed for use in individuals with tissue damage suffered from congenital disorders, infection, irradiation, or cancer. However, in those patients, abnormal cells obtained by biopsy from the compromised tissue could potentially contaminate the engineered...
متن کاملRegenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens.
BACKGROUND Ex vivo expansion of resident cardiac stem cells, followed by delivery to the heart, may favor regeneration and functional improvement. METHODS AND RESULTS Percutaneous endomyocardial biopsy specimens grown in primary culture developed multicellular clusters known as cardiospheres, which were plated to yield cardiosphere-derived cells (CDCs). CDCs from human biopsy specimens and fr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Thoracic and Cardiovascular Surgeon
سال: 2017
ISSN: 0171-6425,1439-1902
DOI: 10.1055/s-0037-1598857